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Working to cure cancer

We are focused on building new therapies for cancer treatment. We identify novel cancer antigens and generate antibodies and cell therapies to target the cancer antigens.   

Publications

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Antibody-drug conjugates for T cell cancers

Our latest publication detailing the development of antibody-drug conjugates for the treatment of T cell leukemias and lymphomas. 

Nature 2024

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Antibodies to treat T cell leukemias and lymphomas

Our study detailing the development of bispecific antibodies that selectively kill T cell cancers and do not harm the normal human T cells.

 

Science Translational Medicine 2021

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Antibody targeting cancers with p53 mutation

​Mutations in p53 tumor suppression gene leads to cancer. We generated an antibody that specifically kills the cancer cells carrying the mutant p53 protein.

 

Science 2021

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Antibodies targeting cancers with RAS mutations

​​Mutations in RAS oncogene lead to cancer. We generated an antibody that specifically kills the cancer cells carrying the mutant p53 protein.

Science Immunology 2021

Links

Location

1650 Orleans Street, CRB1, Room 3M90, Baltimore, MD 21287

Contacts

419-614-3900

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Research Support

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